Table 3.
Relative quantification of AEBSF-modified peptides (ND not detected)
| AEBSF-modified amino acid sites | % AEBSF modification | ||
|---|---|---|---|
| Tyr177 in light chain | Lys250 in Fd | ||
| Negative Control | ND | ND | |
| Positive control | Day 3 | 29.7 | 27.5 |
| Day 7 | 66.5 | 31.7 | |
| Test articles | Lot #1 | 4.4 | 3.3 |
| Lot #2 | 6.5 | 2.3 | |