Scheme 6.
Reagents and conditions. (a) DIPEA, DMF, 90 °C; (b) TFA, DCM, rt; (c) i. carbonyldiimidazole, TEA, DCM, rt; ii. 18, DIPEA, rt; (d) i. 1,1’-thiocarbonyldiimidazole, TEA, DCM, rt; ii. 18, DIPEA, rt.
Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.