Table 2.

Summary of meta-analysis of safety outcomes

Outcome	Studies	Participants	Statistical method	Effect estimate	P-value	I2(%)	Evidence quality
Serious adverse event	2 [22,25]	92	Odd ratio (M-H, Fixed, 95% CI)	0.894 [0.102, 7.808]	0.919	0	Low
Treatment discontinuation due to adverse event	2 [22,25]	92	Odd ratio (M-H, Fixed, 95% CI)	4.288 [0.539, 34.141]	0.169	34.2	Moderate