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. 2020 Aug 17;20:771. doi: 10.1186/s12885-020-07277-3

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© The Author(s) 2020

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 1 — Differentially expressed autophagy-related genes (ARGs) between hepatocellular carcinoma (HCC) and normal samples. a A total of 222 HCC-related ARGs are represented in the volcano plot. Red points indicate upregulated ARGs, while green points represent downregulated ARGs in HCC, compared with normal tissue samples. b Hierarchical clustering of 62 differentially expressed ARGs in HCC, compared with normal tissue samples. Intensities of red and green colors indicate higher or lower gene expression, respectively. c The expression profile of ARGs in HCC and corresponding non-tumor samples. Red boxplots represent gene expression distribution in tumor tissue samples, while green boxplots represent gene expression distribution in normal tissue samples. These plots were created using R software v3.6.1