TABLE 2.
Haemostatic and inflammatory variables in the canine parvovirus group, canine parvovirus subgroups and control group at admission and post fluid resuscitation.
| Variable | Reference interval for adult dogs | Control dogs (N = 15) | Admission |
Post fluid resuscitation |
||||
|---|---|---|---|---|---|---|---|---|
| CPV (N = 27) | Hypovolaemic CPV (N = 16) | Dehydrated CPV (N = 11) | CPV (N = 27) | Hypovolaemic CPV (N = 16) | Dehydrated CPV (N = 11) | |||
| HCT (L/L) | ||||||||
| Median | 0.37–0.55 | 0.35 | 0.44* | 0.44 | 0.43 | 0.37******** | 0.39*********** | 0.35**** |
| IQR | - | 0.22–0.43 | 0.35–0.48 | 0.35–0.52 | 0.35–0.48 | 0.34–0.42 | 0.32–0.42 | 0.33–0.42 |
| Platelet count (x 109/L) | ||||||||
| Median | 200–500 | 325 | 296 | 296 | 292 | 301****** | 309 | 301 |
| IQR | - | 276–463 | 230–427 | 222–477 | 253–402 | 235–383 | 206–409 | 235–318 |
| R (min) | ||||||||
| Median | 2.0–11.0 | 4.9 | 8.9** | 9.2**** | 7.9 | 7.4****** | 7.6 | 7.3 |
| IQR | - | 2.4–7.6 | 6.9–10.4 | 7.4–10.9 | 5.7–9.6 | 5.8–9.3 | 6.2–10.1 | 5.4–7.9 |
| K (min) | ||||||||
| Median | 1.0–5.0 | 1.4 | 2.2* | 2.5*** | 2.0 | 2.0****** | 2.0 | 1.8 |
| IQR | - | 0.8–2.6 | 1.8–3.1 | 2.1–3.3 | 1.5–2.7 | 1.4–2.6 | 1.5–3.1 | 1.2–2.3 |
| α-angle (degrees) | ||||||||
| Median | 34.0–77.0 | 70.7 | 61.5* | 58.4 | 62.6 | 65.3****** | 64.8 | 65.3 |
| IQR | - | 56.6–78.4 | 53.2–65.9 | 54.3–65.5 | 53.2–67.5 | 60.5–71.2 | 53.5–70.4 | 61.8–73.8 |
| MA (mm) | ||||||||
| Median | 42.0–7.1 | 67.0 | 77.0** | 77.2**** | 76.0*** | 78.3******* | 80.8********** | 78.1 |
| IQR | - | 56.3–70.1 | 72.1–80.3 | 73.4–80.0 | 69.2–81.7 | 75.9–82.2 | 76.2–82.7 | 75.9–80.1 |
| AT (% activity) | ||||||||
| Median | 80–100 | 80.2 | 81.2 | 82.1 | 80.8 | 76.3******** | 74.7********** | 82.1********* |
| IQR | - | 71.5–88.9 | 77.2–88.6 | 77.4–90.1 | 76.3–88.6 | 70.3–83.0 | 70.2–79.3 | 71.5–83.3 |
| Fibrinogen (mg/dL) | ||||||||
| Median | 200–300 | 276 | > 700** | > 700***** | > 700***** | > 700***** | > 700 | > 700 |
| IQR | - | 250–360 | - | - | - | - | - | - |
| CRP (mg/L) | ||||||||
| Median | 0–10.0 | 6.43 | 135.10** | 135.60***** | 133.40***** | 117.9****** | 96.4********* | 88.8********** |
| IQR | - | 4.74–12.76 | 98.95–155.07 | 105.00–155.00 | 76.00–155.50 | 103.38–148.23 | 75.4–136.6 | 52.8–106.9 |
Note: CPV subgroups at admission and after fluid resuscitation.
CPV, canine parvovirus; IQR, interquartile range; HCT, haematocrit; R, reaction time; K, clot formation time; MA, maximum amplitude; AT, antithrombin; α-angle, rapidity of fibrin build-up and cross-linking.
Significant difference: *, p < 0.05; **, p < 0.001, between control and CPV group at admission.
Significant difference: ***, p < 0.05; ****, p = 0.001; ^*****, p < 0.001 between control and CPV subgroups at admission.
Significant difference: ******, p < 0.05; *******, p < 0.01; ********, p < 0.001 between CPV group at admission and after fluid resuscitation.
Significant difference: *********, p < 0.05; **********, p < 0.01; ***********, p < 0.001 within CPV subgroups at admission and after fluid resuscitation.