SUPPLEMENTARY TABLE 7.

Variants with clinical significance (n = 136609)

Clinical effect	20 genomes average	12 most covered genomes average	% based on 20 genomes
Benign	4979.6	6725.5	72.9
Likely benign	1274.2	1766.2	18.7
Other	242.7	333.8	3.6
Uncertain significance	153.1	222.9	2.2
Not provided	87.6	122.3	1.3
Drug response	48.7	64.5	0.7
Pathogenic	37.4	51.0	0.5
Likely pathogenic	7.4	10.5	0.1