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. Author manuscript; available in PMC: 2020 Aug 18.
Published in final edited form as: Cell Rep. 2020 Aug 4;32(5):107998. doi: 10.1016/j.celrep.2020.107998

Figure 1. 2D Representation of 3D Data Related to Whole iWAT Depots Reveals Robust UCP1 Upregulation in the iAdFASNKO Mouse.

Figure 1.

All panels are light-sheet fluorescence microscopy images of inguinal white adipose tissue (iWAT) processed using the Adipo-Clear technique.

(A and B) 2D representations of 3D reconstruction of adipose sympathetic nerves and thermogenic profile of iWAT from control, iAdFASNKO, and 6°C cold-exposed mice (A). The samples are immunolabeled with anti-TH (green) and anti-UCP1 (orange) and imaged at (A) 1.1× and (B) 24× magnification. Scale bars are provided for each panel.