3.
miR-141、miR-200a、miR-205、miR-143、miR-145在汉族女性EEC (n=53)和NEEC (n=29)中的表达
Expression of miR-141, miR-200a, miR-205, miR-143, and miR-145 in the Han women with EEC (n=53) or NEEC (n=29)
| Variable | log2 (relative quantity), mean±SE | |||||||||
| miR-141 | miR-200a | miR-205 | miR-143 | miR-145 | ||||||
| a, 81 Han women received hysterectomy; b, 40 Han women received lymphadenectomy. Abbreviations as in Table 2. | ||||||||||
| EEC | NEEC | EEC | NEEC | EEC | NEEC | EEC | NEEC | EEC | NEEC | |
| Histologic type | 2.63±0.34 | 4.82±1.01 | 2.61±0.38 | 5.81±1.30 | 4.51±0.52 | 4.31±0.79 | -2.43±0.34 | -0.13±1.16 | -2.61±0.32 | -2.70±0.92 |
| P | 0.023 | <0.001 | <0.001 | <0.001 | 0.012 | 0.015 | <0.001 | 0.009 | 0.001 | 0.187 |
| Age | ||||||||||
| Premenopause (n=28) | 2.78±0.56 | 4.79±1.84 | 1.76±0.70 | 8.21±1.64 | 4.97±0.84 | 5.18±1.55 | -2.22±0.53 | -2.54±1.34 | -1.94±0.53 | 0.84±2.81 |
| Postmenopause (n=54) | 2.55±0.43 | 4.62±0.98 | 3.12±0.42 | 5.03±1.31 | 4.23±0.67 | 4.35±0.71 | -2.85±0.39 | -1.73±0.69 | -2.73±0.44 | 0.01±0.83 |
| P | 0.751 | 0.934 | 0.082 | 0.247 | 0.499 | 0.606 | 0.334 | 0.596 | 0.267 | 0.702 |
| Grade (EEC) | ||||||||||
| Low (n=28) | 2.60±0.46 | - | 2.64±0.42 | - | 3.89±0.80 | - | -2.39±0.46 | - | -2.36±0.37 | - |
| High (n=25) | 2.68±0.51 | - | 2.43±0.86 | - | 5.20±0.64 | - | -2.86±0.43 | - | -2.92±0.80 | - |
| P | 0.907 | 0.694 | 0.212 | 0.470 | 0.446 | |||||
| Myometrial invasiona | ||||||||||
| <1/2 (n=62) | 2.55±0.43 | 4.62±0.98 | 2.63±0.41 | 5.43±1.49 | 4.67±0.54 | 4.40±0.71 | -2.32±0.35 | -2.43±0.82 | -2.26±0.36 | -0.73±1.33 |
| ≥1/2 (n=19) | 2.88±0.46 | 4.31±1.95 | 2.55±0.81 | 7.08±3.16 | 4.06±1.30 | 3.95±1.56 | -3.41±0.66 | -1.70±0.85 | -2.90±0.83 | 1.91±2.22 |
| P | 0.603 | 0.876 | 0.817 | 0.614 | 0.609 | 0.762 | 0.129 | 0.609 | 0.431 | 0.160 |
| Lymph node metastasesb | ||||||||||
| No (n=32) | 2.72±0.58 | 5.05±1.20 | 3.19±0.63 | 5.70±2.05 | 4.35±1.12 | 4.53±0.85 | -2.15±0.58 | -1.92±0.89 | -1.84±0.69 | -0.02±1.57 |
| Yes (n=8) | 2.29±1.32 | 5.21±0.90 | 2.71±1.69 | 6.36±1.35 | 4.02±1.13 | 2.00±1.65 | -2.82±0.79 | -4.97±1.90 | -2.51±1.05 | -3.23±1.71 |
| P | 0.738 | 0.956 | 0.411 | 0.671 | 0.879 | 0.229 | 0.567 | 0.172 | 0.457 | 0.457 |
| Vessel invasiona | ||||||||||
| No (n=67) | 2.69±0.38 | 4.47±1.03 | 2.77±0.38 | 5.68±1.57 | 4.48±0.61 | 4.39±0.78 | -2.45±0.36 | -2.54±0.76 | -2.35±0.37 | -0.35±1.44 |
| Yes (n=14) | 2.37±0.78 | 4.78±1.70 | 1.84±1.25 | 6.42±2.81 | 4.65±0.70 | 3.80±1.19 | -3.40±0.62 | -0.96±0.67 | -2.81±0.88 | 0.93±0.90 |
| P | 0.733 | 0.891 | 0.255 | 0.867 | 0.906 | 0.727 | 0.260 | 0.322 | 0.602 | 0.073 |
| Stagea | ||||||||||
| Ⅰ or Ⅱ (n=68) | 2.63±0.37 | 3.81±0.99 | 2.71±0.38 | 4.53±1.60 | 4.49±0.59 | 4.21±0.66 | -2.45±0.34 | -1.83±0.70 | -2.27±0.36 | -0.42±1.28 |
| Ⅲ or Ⅳ (n=13) | 2.67±0.94 | 6.97±1.73 | 1.98±1.53 | 9.77±1.91 | 4.64±0.87 | 4.49±1.96 | -3.64±0.77 | -3.56±1.38 | -3.51±0.97 | 0.98±2.63 |
| P | 0.970 | 0.134 | 0.587 | 0.570 | 0.925 | 0.862 | 0.204 | 0.252 | 0.172 | 0.507 |