3.

静息心率及常见慢性病单表型遗传度

Univariate heritability of resting heart rate and common chronic diseases

Variables	Effect of covariatesa	Heritability (95%CI)	P
a, covariates include gender, age, age×gender, age2, gender×age2; b, inverse normal transformation was applied for the variables not following normal distribution. SBP, systolic blood pressure; DBP, diastolic blood pressure; HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol; CI, confidence interval.
Resting heart rate	0.022	0.263 (0.120-0.407)	<0.001
Hypertension	-	0.404 (0.135-0.673)	0.001
Diabetes	-	0.272 (-0.164-0.708)	0.11
Dyslipidemia	-	0.799 (0.590-1.000)	<0.001
SBP	0.187	0.379 (0.213-0.545)	<0.001
DBP	0.069	0.306 (0.155-0.458)	<0.001
Fasting glucoseb	0.054	0.393 (0.244-0.543)	<0.001
Total cholesterolb	0.034	0.452 (0.306-0.598)	<0.001
Triglycerideb	0.040	0.568 (0.429-0.707)	<0.001
HDL-Cb	0.037	0.852 (0.741-0.964)	<0.001
LDL-C	0.042	0.387 (0.236-0.538)	<0.001