2.

546例结直肠间质瘤单因素预后分析

Univariate survival analyses of 546 patients with colorectal stromal tumor

Variables	n	CSS		P	OS		P
		5-year survival rate/%	10-year survival rate/%		5-year survival rate/%	10-year survival rate/%
*, tumor size was not collected in SEER database before 2004; SEER, surveillance, epidemiology, and end results; LNM, lymph node metastasis; CSS, cancer-specific survival; OS, overall survival.
Age/years				< 0.001			< 0.001
≤ 64	273	85.2	76.8		79.1	66.5
> 64	273	71.4	56.3		49.4	25.0
Gender				0.792			0.934
Male	302	78.7	67.5		64.8	46.1
Female	244	78.8	68.4		63.6	46.0
Marital status				0.027			0.007
Married	321	80.6	70.6		67.8	50.1
Single/Divorced	192	73.8	61.2		56.8	38.5
Unknown	33	88.6	78.8		74.4	45.5
Ethnicity				0.154			0.035
Caucasian	361	75.9	65.9		59.7	44.0
African-American	93	87.1	74.5		73.8	48.6
Other/Unknown	92	80.7	67.7		72.6	49.5
Date range/year				0.146			0.733
1992-2007	276	76.0	66.7		62.5	46.5
2008-2015	270	82.6	70.0		66.1	43.7
SEER registry in America				0.029			0.063
Eastern	238	81.8	76.9		68.7	52.7
Western	308	76.3	62.9		61.0	42.2
Tumor location				0.002			< 0.001
Colon	241	69.1	60.6		53.4	41.0
Rectum	280	86.6	74.2		73.9	53.5
Unknown	25	84.8	68.9		66.2	12.1
Surgery or not				< 0.001			< 0.001
No/Unknown	118	61.3	31.7		38.9	20.1
Surgery	428	82.1	73.3		70.6	51.7
Differentiation grade				< 0.001			< 0.001
Ⅰ	35	97.1	83.3		93.5	74.8
Ⅱ	56	90.1	84.1		82.9	71.0
Ⅲ	34	55.8	55.8		41.5	26.0
Ⅳ	54	67.8	40.5		48.5	22.2
Unknown	367	79.4	68.5		64.0	47.3
Tumor size/cm*				0.001			< 0.001
≤2	65	95.0	95.0		82.8	77.6
>2-5	89	89.4	61.3		73.8	48.5
>5-10	120	83.3	76.8		69.9	55.7
>10	50	74.9	59.0		61.9	37.5
Unknown	222	69.7	61.6		54.7	38.8
Lymphadenectomy				0.325			0.652
No/Unknown	342	82.2	69.7		65.4	47.5
Yes	204	75.0	66.9		62.4	45.1
LNM				< 0.001			< 0.001
Negative/Unknown	527	79.7	70.6		65.2	48.4
Positive	19	41.9	20.9		38.3	6.4
Distant metastasis				< 0.001			< 0.001
No/Unknown	499	81.9	71.3		67.5	48.6
Yes	47	32.6	32.6		23.6	23.6