2.
IMNM不同抗体组实验室特征比较
Comparisons of laboratory characteristics of different serological subgroups of IMNM
| Features a | IMNM (n=104) | Anti-SRP (n=47) | Anti-HMGCR (n=23) | MSAs negative (n=34) | P |
| ANA, anti-nuclear antibodies; ALT, alanine aminotransferase; AST, aspartate aminotransferase; LDH, lactic dehydrogenase; CK, creatine kinase; CRP, C reactive protein; ESR, erythrocyte sedimentation rate; Fet, serum ferritin; other abbreviations as in Table 1. a, normal value in brackets. Data are shown as n(%) and median (IQR). * P<0.017, between anti-SRP and anti-HMGCR/MSAs negative group; # P<0.017, between anti-SRP and anti-HMGCR group; △ P<0.05, between anti-SRP and MSAs negative group. | |||||
| Anti-Ro-52 | 25 (24.0) | 16 (34.0) | 1 (4.3) | 8 (23.5) | 0.024 |
| ANA | 74/101 (73.3) | 42/45 (93.3) | 8/22 (36.4) | 20/34 (58.8) | <0.001* |
| Peak CK/(IU/L) | 5 100 (2 749, 9 916) | 5 070 (2 975, 9 994) | 5 728 (3 320, 11 435) | 4 827 (1 324, 9 831) | 0.546 |
| ALT (0-40 U/L) | 96 (51, 208) | 120 (55, 221) | 93 (51, 209) | 92 (38, 154) | 0.500 |
| AST (0-40 U/L) | 62 (36, 127) | 83 (37, 151) | 64 (36, 124) | 54 (29, 114) | 0.306 |
| LDH (100-250 IU/L) | 522 (317, 770) | 587 (339, 783) | 569 (330, 836) | 387 (258, 615) | 0.113 |
| CK (26-200 IU/L) | 2 157 (810, 4 645) | 1 753 (771, 4 241) | 2 157 (861, 5 481) | 2 326 (612, 4 709) | 0.956 |
| CRP (<8 mg/L) | 2.9 (1.9, 5.5) | 2.9 (1.9, 5.2) | 4.3 (2.2, 8.6) | 2.6 (1.6, 5.2) | 0.198 |
| ESR (<20 mm/h) | 8 (4, 16) | 9 (4, 20) | 8 (4, 20) | 6 (3, 13) | 0.466 |
| Fet (11.0-306.8 μg/L) | 123.0 (48.9, 231.1) | 120.0 (58.9, 218.2) | 172.0 (109.9, 716.7) | 86.0 (22.0, 205.0) | 0.126 |
| IgG (6.94-16.20 g/L) | 10.50 (8.28, 14.13) | 11.60 (8.73, 15.65) | 8.59 (6.03, 11.28) | 10.50 (8.87, 13.40) | 0.033# |
| IgA (0.68-3.78 g/L) | 1.67 (1.17, 2.35) | 1.86 (1.35, 2.58) | 1.32 (1.03, 1.92) | 1.56 (0.09, 2.54) | 0.105 |
| IgM (0.60-2.63 g/L) | 1.12 (0.79, 1.45) | 1.19 (0.82, 1.76) | 0.88 (0.66, 1.21) | 1.18 (0.84, 1.42) | 0.109 |
| C3 (0.70-1.28 g/L) | 0.86 (0.75, 1.01) | 0.87 (0.77, 0.99) | 0.88 (0.78, 1.05) | 0.82 (0.71, 1.03) | 0.336 |
| C4 (0.16-0.47 g/L) | 0.18 (0.15, 0.22) | 0.19 (0.15, 0.23) | 0.20 (0.17, 0.24) | 0.17 (0.12, 0.20) | 0.067 |
| T cell (1 000-3 000 cell/mL) | 2 060 (1 555, 2 650) | 1 870 (1 480, 2 240) | 1 990 (1 370, 2 350) | 2 620 (1 570, 3 350) | 0.027△ |
| CD3+ T cell (808-2 072 cell/mL) | 1 500 (1 038, 1 877) | 1 400 (999, 1 686) | 1 458 (903, 1 978) | 1 767 (1 125, 2 378) | 0.760 |
| CD4+ T cell (380-1 280 cell/mL) | 853 (608, 1 283) | 817 (604, 1 114) | 758 (456, 1 123) | 1 767 (1 125, 2 378) | 0.042 |
| CD8+ T cell (229-982 cell/μL) | 493 (375, 761) | 477 (378, 678) | 653 (345, 797) | 554 (348, 812) | 0.586 |