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7例原发性纵隔卵黄囊瘤临床资料
The clinical manifestations of seven primary mediastinal yolk sac tumor patients
Case | Age/years | Symptom | AFP before chemotherapy/ (μg/L) |
Preoperative chemotherapy (cycle, drug) |
AFP after chemotherapy/ (μg/L) |
Surgical approach |
Excision extension |
Surgical margin |
Subtype | Postoperative chemotherapy (cycle, drug) |
Recurrence location |
Status* | Survival/ months |
AFP, alpha fetoprotein; PEB, cisplatin+etoposide+bleomycin; EP, cis-platin+etoposide; R0, no cancer cells seen microscopically; R1, cancer cells present microscopically; SVCS, superior vena cava syndrome; LMSAT, left muscle-sparing axillary thoracotomy; MS, median sternotomy; RMSAT, right muscle-sparing axillary thoracotomy. *at the time of June 2019. | |||||||||||||
1 | 16 | Chest distress fever | 9 545.00 | 4×PEB | 4.84 | LMSAT | Tumor+partial pericardium+ phrenic nerve |
R0 | Not clear | 2×PEB | No | Alive | 48 |
2 | 17 | Chest distress chest pain | 285.50 | 4×EP | 13.31 | MS | Tumor+partial pericardium+ partial pulmonary |
R0 | Microcyst | 2×PEB | Pulmonary | Alive | 39 |
3 | 32 | No | 2 697.00 | - | - | RMSAT | Tumor+partial pericardium | R0 | Adenoid | 4×PEB | Pulmonary | Dead | 11 |
4 | 35 | Chest distress SVCS | 12 045.00 | 6×PEB | 1 117.00 | MS | Tumor+partial pericardium and pulmonary+superior vena cava |
R1 | Hybird | No | Pulmonary | Dead | 5 |
5 | 14 | Cough chest pain | 32 105.00 | 6×PEB | 10.91 | RMSAT | Tumor+thymoma | R0 | Giant capsule | 2×PEB | No | Alive | 23 |
6 | 22 | Cough | 1 210.00 | - | - | LMSAT | Tumor+ phrenic nerve | R0 | Hybird | 4×EP | No | Alive | 15 |
7 | 22 | Fever chest pain | 42 034.00 | 2×PEB | 261.60 | MS | Tumor+partial pericardium and pulmonary+superior vena cava |
R0 | Not clear | 4×PEB | No | Alive | 13 |