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血浆游离型MNs正常的PPGL患者的临床特点
Clinical features in PPGL patients with normal plasma free MNs
| Case | Gender | Age/years | Reasons for consultation | Symptoms | Hypertension | BMI/(kg/m2) | Tumor location | Tumor diameter/cm | Typical findings on enhanced CT | Functional imaging | Preoperative laboratory test | ||
| MN/(nmol/L) | NMN/(nmol/L) | 3-MT/(nmol/L) | |||||||||||
| MNs, metanephrines; NMN, normetanephrine; BMI, body mass index; PPGL, pheochromocytoma and paraganglioma; 3-MT, 3-methoxytyramine; F, female; M, male; ND, not done; 99mTc-TOC, 99mTc-octreo-tide; PET, positron emission tomography; MIBG, 123I-metaiodobenzylguanidine. Reference interval：MN≤0.50 nmol/L, NMN≤0.90 nmol/L, 3-MT＜0.18 nmol/L. | |||||||||||||
| 1 | F | 40 | Follow-up after surgery | Fatigue | Persistent | 26.24 | Adrenal | 1.5 | No | ND | 0.11 | 0.29 | ＜0.08 |
| 2 | F | 70 | Typical symptoms | Sweating, dizziness, fatigue | Persistent | 24.88 | Adrenal | 1.5 | No | PET-CT (+) | 0.20 | 0.50 | ＜0.08 |
| 3 | F | 62 | Typical symptoms | Palpitations, sweating, abdominal pain | Paroxysmal | 27.85 | Retroperitoneal | 5 | Yes | ND | 0.22 | 0.59 | ＜0.08 |
| 4 | M | 66 | Typical symptoms | Headache, palpitations, sweating | Persistent | 26.30 | Retroperitoneal | 1.2 | No | ND | 0.19 | 0.71 | ＜0.08 |
| 5 | F | 25 | Typical symptoms | Headache, nausea | Paroxysmal | 22.56 | Adrenal | 4.5 | Yes | ND | 0.05 | 0.20 | 2.27↑ |
| 6 | F | 23 | Adrenal incidentaloma | Asymptomatic case | Paroxysmal | 27.73 | Adrenal | 6 | Yes | 99mTc-TOC (+) | 0.03 | 0.37 | 0.23↑ |
| 7 | M | 64 | Atypical symptoms | Back pain | Paroxysmal | 23.14 | Adrenal | 5 | Yes | ND | 0.11 | 0.42 | ＜0.08 |
| 8 | F | 35 | Follow-up after surgery | Back pain | Normal blood pressure | 17.67 | Adrenal | 5.5 | Yes | PET-CT (+) MIBG (-) | 0.05 | 0.31 | ND |