Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2020 Sep;27(9):380–389. doi: 10.1101/lm.050666.119

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2020 Fontaine et al.; Published by Cold Spring Harbor Laboratory Press

This article is distributed exclusively by Cold Spring Harbor Laboratory Press for the first 12 months after the full-issue publication date (see http://learnmem.cshlp.org/site/misc/terms.xhtml). After 12 months, it is available under a Creative Commons License (Attribution-NonCommercial 4.0 International), as described at http://creativecommons.org/licenses/by-nc/4.0/.

PMC Copyright notice

Figure 4. — Establishment of LTD by 6000 × 10 Hz does not occlude further LTD induced by 900 × 1 Hz. The magnitudes of LTD by any form of conditioning stimulus were determined from the average percent change in the fEPSP slope of the last 5 min of each postconditioning recording relative to the original baseline. (A) Following 40 min of postconditioning recordings after 6000 × 10 Hz (gray arrow; A), 900 × 1 Hz LFS was delivered (white arrow) followed by a second postconditioning recording for 30 min. The average magnitudes of each LTD are represented in B for each corresponding experiment. 6000 × 10 Hz LTD (−21.23 ± 3.67%, n = 11 slices) did not occlude further LTD by 900 × 1 Hz LFS (−37.99 ± 5.02%, P = 0.00176). (B) Bars represent average magnitudes of LTD induced by each conditioning stimulus. Dots represent the average amounts of LTD for each slice that make up the average (indicated as the bar) for each group. Error bars throughout represent the standard error of the mean. Statistical significance was achieved by a two-tailed t-test compared against control and P < 0.05 is indicated by a *.