FIGURE 3.
Variant allele frequencies (VAF) in bone marrow from baseline (Day 0) to count recovery (Day 30). Variants with allelic frequency less than 5% on Day 0 were excluded from analysis (non-detectable or ND). The lower-limit of detection of variants at Day 30 was ∼ 0.1% for those identified at baseline and ∼ 2.7% for those that were newly detected. Trendlines indicate variants increasing (red), decreasing (green), or remaining stable (black) through induction chemotherapy and MST. A–C, correspond with patients who developed a complete remission after induction therapy, while, D,E, correspond with patients who had refractory disease after induction therapy