Table 2. Calculated TEC Values of TFV, FTC, EFV, and RPV for Murine Tissues (Liver, Brain, Kidney, Spleen, and Heart) and Predicted log P Values.

compound	TEC in liver tissue	TEC in brain tissue	TEC in kidney tissue	TEC in spleen tissue	TEC in heart tissue	log P value
TFV	0.0769	0.0082	0.0097	0.0048	0.0110	–1.74
FTC	0.0401	0.0174	0.0017	0.0009	0.0061	–0.65
EFV	0.0358	0.1300	0.0045	0.0153	0.0319	4.15
RPV	0.0094	0.2377	0.0633	0.0436	0.0161	4.64