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Fig. 8. Chemical structures of small molecule inhibitors of signal transducer and activator of transcription 3: L61H46 (53), PG-S3-001 (54), HJC0416 (55), XZH-5 (56), methyl N-(((3,5-bis(trifluoromethyl)phenyl)-carbamoyl)isoleucyl)-N‘-methyl-l-histidinate (57) and cryptotanshinone (58).