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. Author manuscript; available in PMC: 2020 Aug 18.
Published in final edited form as: Cell Rep. 2020 Jun 16;31(11):107778. doi: 10.1016/j.celrep.2020.107778

Figure 1. Sharpened Birth-Dating with 4-OHT.

Figure 1.

(A) In Dlx1::CreER/Ai14 reporter mice, cells are permanently labeled by tdTomato only if 4-OHT has been administered when the Dlx1 promoter is active, i.e., the neurogenetic phase of striatal progenitors.

(B) 4-OHT was administered at successive developmental times, separated by a single day.

(C) Striatum of 4-OHT pulse-labeled mice was assessed at maturity. Coronal sections in upper panels were stained for tdTomato (red), CalDAG-GEFI (CDG1, green), and MOR1 (blue). Lower panels show individual channels in grayscale.