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. 2020 Jul 1;9(16):5827–5838. doi: 10.1002/cam4.3259

FIGURE 1.

FIGURE 1

Design of chimeric antigen receptor (CAR) targeting CD19 and CD20. (A) Schematic of anti‐CD19 CAR and anti‐CD20 CAR. Single‐chain (sc) Fv region recognizes CD19 or CD20, CAR contained 4‐1BB costimulatory domain and CD3‐ζ T cell activation domain. (B) Fludarabine combined with cyclophosphamide was used as the pretreatment regimen. Cells were ready for infusion on day 0