TABLE 4.
Prognosis factors for renal cell carcinoma patients with venous tumor thrombus
| Items | Univariable analysis | Multivariable analysis | ||||
|---|---|---|---|---|---|---|
| HR | 95% CI | P value | HR | 95% CI | P value | |
| M1 stage | 3.499 | 1.726‐7.091 | <.001 | 3.356 | 1.488‐7.568 | .004 |
| Mayo classification | 2.207 | 1.439‐3.385 | <.001 | — | — | .830 |
| Maximum width of tumor thrombus | 1.158 | 1.085‐1.236 | <.001 | — | — | .986 |
| Operative approach | 2.157 | 1.023‐4.547 | .043 | — | — | .884 |
| IVC resection | 6.900 | 2.336‐20.379 | <.001 | — | — | .361 |
| Operative time | 1.007 | 1.003‐1.011 | .001 | — | — | .761 |
| Surgical bleeding volume | 1.000 | 1.000‐1.001 | .001 | 1.000 | 1.000‐1.001 | .043 |
| Surgical blood transfusion volume | 1.001 | 1.000‐1.001 | .001 | — | — | .654 |
| Plasma transfusion volume | 1.001 | 1.000‐1.002 | .002 | — | — | .915 |
| The width of tumor thrombus at the entrance of the renal vein | 1.236 | 1.109‐1.379 | <.001 | 1.220 | 1.089‐1.366 | .001 |
| Sarcomatoid differentiation | 4.039 | 1.962‐8.314 | <.001 | 6.875 | 2.907‐16.260 | <.001 |
| Clear cell RCC | 2.850 | 1.337‐6.075 | .007 | 3.171 | 1.257‐7.999 | .015 |
| Elevated alkaline phosphatase | 3.120 | 1.474‐6.604 | .003 | 2.543 | 1.102‐5.869 | .029 |
| BT | 2.271 | 1.008‐5.121 | .048 | 3.323 | 1.378‐8.012 | .007 |
Abbreviations: BT, bland thrombus; CI, confidence interval; HR, hazard ratio; RC, renal cell carcinoma.