TABLE 4.

A 25-Year-Old Woman With Stage IIA Nodular Sclerosing Hodgkin Lymphoma With Bilateral Supraclavicular and Mediastinal (7 cm in Widest Diameter) Involvement; Normal ESR. Interim PET/CT is Negative (Deauville 2)

Treatment	Rating	Comments
Radiation alone	2
Chemotherapy and ISRT	9
Chemotherapy and IFRT	6
Chemotherapy alone	5	This option may be appropriate but there was disagreement among panel members on the appropriateness rating as defined by the panel’s median rating
Type of chemotherapy
ABVD	9
Stanford V (8 wk course)	7
Stanford V (12 wk course)	5
Duration of ABVD (if chemotherapy given alone)
2 cycles	1
4 cycles	5	This option may be appropriate but there was disagreement among panel members on the appropriateness rating as defined by the panel’s median rating
6 cycles	7
Duration of ABVD (combined modality)
2 cycles	5	This option may be appropriate but there was disagreement among panel members on the appropriateness rating as defined by the panel’s median rating
4 cycles	8
6 cycles	5	This option may be appropriate but there was disagreement among panel members on the appropriateness rating as defined by the panel’s median rating
Dose of radiation therapy (combined modality)
20 Gy	5	This option may be appropriate but there was disagreement among panel members on the appropriateness rating as defined by the panel’s median rating
30 Gy	7
30 Gy + 6 Gy boost to mediastinum	5

Rating scale: 1, 2, 3 usually not appropriate; 4, 5, 6 may be appropriate; 7, 8, 9 usually appropriate.

ABVD indicates doxorubicin, bleomycin, vinblastine, and dacarbazine; ESR, erythrocyte sedimentation rate; IFRT, involved field radiation therapy; ISRT, involved site radiation therapy; PET/CT, positron emission tomography/computed tomography.