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. 2020 Jul 30;16(7):e1008904. doi: 10.1371/journal.pgen.1008904

Fig 5. CMT-1 is required for the synapsis checkpoint.

Fig 5

A. Cartoon of meiotic checkpoint activation in C. elegans. B. Mutation of cmt-1 reduces apoptosis in syp-1 single mutants and syp-1;spo-11 double mutants. Error bars indicate 2XSEM. C. pch-2E253Q reduces apoptosis in syp-1 and syp-1;spo-11 mutants but not in syp-1;cmt-1 or syp-1;spo-11;cmt-1 mutants. Significance was assessed by performing two-tailed t-tests. A *** indicates a p value < 0.0001, a ** indicates a p value < 0.01 and an n.s. indicates not significant.