Fig 6. cmt-1 mutants delay pairing, accelerate synapsis and exhibit non-homologous synapsis, similar to pch-2^E253Q mutants.

A. Timecourse of pairing in wildtype and cmt-1 mutant germlines. B. Timecourse of synapsis in wildtype and cmt-1 mutant germlines. C. Images of meiotic nuclei stained with antibodies against HTP-3, SYP-1 and HIM-8 in cmt-1 and cmt-1;pch-2Δ mutants. The circled nucleus has undergone non-homologous synapsis. D. Quantification of non-homologous synapsis wildtype animals, cmt-1, cmt-1;pch-2^E253Q and cmt-1;pch-2Δ mutants. All error bars indicate 95% confidence intervals. Significance was assessed by performing two-tailed Fisher exact tests. A *** indicates a p value < 0.0001.