Figure 2.

Neurons use endocannabinoid signaling to activate astrocyte Ca²⁺ signaling pathways. A, Representative bright-field image from a single slice in which the white arrow indicates the placement of the microelectrode tip. B, Representative intensity changes before and after depolarization of an SCN neuron (indicated by black bar) before (left, control) and during (right) AM251 treatment. White scale bar: 50 μm; images taken at 40×. (Adapted from Figure 5 in Hablitz et al., 2020.)