Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2020 Jul 23;12:6195–6207. doi: 10.2147/CMAR.S254784

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2020 Liu et al.

This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php).

PMC Copyright notice

The effects of fucoidan on OC cells apoptosis. (A) Nuclear fragmentation of SKOV-3 and Caov-3 cells was observed by fluorescence microscopy and staining with Hoechst 33,342 dye (magnification, 200 ×). (B) Apoptosis of SKOV-3 and Caov-3 cells was determined by flow cytometry. (C) Western blot analysis was performed to determine the levels of proteins related to cell apoptosis. The data are expressed as the mean ± SD (n=3, *p < 0.05 for Fu25 vs Control; ^#p < 0.05 for Fu50 vs Fu25; and ^{^}p < 0.05 for Fu100 vs Fu50). (D) SKOV-3 and Caov-3 cells were pretreated with or without 50 μM of the pan-caspase inhibitor Z-VAD-FMK for 1 h. Western blot analysis was performed to determine the levels of Cyto C of mitochondria and cytoplasm. The data are expressed as the mean ± SD (n=3, *p < 0.05 for Fu100 vs Fu100+Z-VAD-FMK, ^{^}p < 0.05 for Z-VAD-FMK vs Fu100+Z-VAD-FMK).