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. 2020 Jul 23;12:6195–6207. doi: 10.2147/CMAR.S254784

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© 2020 Liu et al.

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The anti-tumor effects of fucoidan in vivo. (A). Gross observation of HCC-SKOV-3 cell xenograft tumors in nude mice. (B and C) Changes in the tumor volume and mouse body weight. (D) Changes in the tumor weights of the experimental mice. The data are expressed as the mean ± SD. (E) Immunohistochemical staining (magnification ×400) of tumors show the levels of Ki-67, Bax and Bcl-2. (F) The levels of proteins related to the apoptosis was detected by Western blot. (n=3, *p < 0.05 Fucoidan-10mg/kg vs Control).