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HSF1 reduces infectivity of newly produced virions. Fold-change in infectious TZM-bl titers per ng of p24 after 96 h of HIV-1 infection at an MOI of 0.04 in CEMcHSF1 and CEMCtrl cells treated with 1 μg/mL dox, relative to vehicle-treated cells. ** and ns correspond to p-values < 0.01 and not significant, respectively.
