Table 4. Cox regression model showing adjusted and unadjusted hazard rates.
| Unadjusted HR (95% CI) | p-value | Adjusted HR (95% CI) | p-value | ||
|---|---|---|---|---|---|
| Tumour size (cm) | |||||
| ≤2 | 0.29 (0.09–0.92) | 0.036 | NA | ||
| 2.01–5 | 0.60 (0.29–1.24) | 0.170 | 1.06 (0.43–2.60) | 0.894 | |
| >5 | 1 | 1 | |||
| Tumour grade | |||||
| Low grade | 1 | 1 | |||
| Intermediate grade | 0.78 (0.44–1.39) | 0.401 | 0.39 (0.17–0.91) | 0.028 | |
| High grade | 0.21 (0.06–0.72) | 0.013 | 0.12 (0.03–0.45) | 0.002 | |
| Resection margin | |||||
| Free | 1 | ||||
| Involved | 1.72 (1.03–2.87) | 0.037 | 1.41 (0.70–2.84) | 0.334 | |
| Evidence of recurrence | |||||
| Yes | 3.21 (1.92–5.36) | <0.001 | 3.69 (1.51–9.02) | 0.004 | |
| No | 1 | ||||
| Harvested nodes | |||||
| 1–3 | 0.19 (0.06–0.63) | 0.006 | 0.43 (0.08–2.20) | 0.308 | |
| 4–9 | 0.40 (0.23–0.68) | 0.001 | 2.16 (0.87–5.39) | 0.098 | |
| ≥10 | 1 | 1 | |||
| Metastatic nodes | |||||
| 0 | 1 | 1 | |||
| 1–3 | 0.61 (0.27–1.37) | 0.235 | 1.46 (0.49–4.37) | 0.496 | |
| 4–9 | 2.19 (1.18–4.04) | 0.013 | 3.61 (1.52–8.60) | 0.004 | |
| ≥10 | 31.62 (11.30–8.47) | < 0.001 | 48.25 (10.17–228.89) | <0.001 | |