Table 4. HPV load and physical status in patients with HNSCC.
| Tumour site | Clinical data | Viral load and physical status of HPV-16 |
|||||
|---|---|---|---|---|---|---|---|
| T | N | HPV | Copies of E6/β-globin | Copies of E2/β-globin | E2/E6 ratio | Physical status of virus | |
| Oropharynx | 4 | 2b | 16, 18 | ND* | 0 | No E2 | Integrated |
| Larynx | 3 | 0 | 16 | 4 | 0 | No E2 | Integrated |
| Larynx | 4 | 3 | 16 | 4 | 0 | No E2 | Integrated |
| Oral cavity | 4 | 0 | 16 | 4 | 0 | No E2 | Integrated |
| Oropharynx | 2 | 0 | 16 | 16 | 5 | 0.8 | Mixed |
| Oral cavity | 3 | 0 | 16 | 9 | 0 | No E2 | Integrated |
| Oropharynx | 4 | 3 | 16 | 20 | 4 | 1.75 | Episomal |
| Oral cavity | 2 | 0 | 16,18,31 | ND* | 0 | No E2 No E6 | NA** |
| Oral cavity | 4 | 2b | 16 | 3 | 0 | No E2 | Integrated |
| Larynx | 2 | 0 | 6,16 | 5 | 0 | No E2 | Integrated |
| Oropharynx | 3 | 0 | 16 | 2 | 0 | No E2 | Integrated |
| Larynx | 4 | 0 | 6,11 and 16 | 3 | 0 | No E2 | Integrated |
| Larynx | 2 | 0 | 6,11 and 16 | 8 | 0 | No E2 | Integrated |
| Oropharynx | 4 | 0 | 11,61 | 10 | 7 | 0.5 | Mixed |
| Oral cavity | 2 | 3 | 6,11 and 16 | ND* | 0 | No E2 No E6 | NA** |
| Oral cavity | 4 | 2b | 11, 16 | 3 | 0 | No E2 | Integrated |
| Oral cavity | 2 | 1 | 6,11 and 16 | 3 | 0 | No E2 | Integrated |
| Hypopharynx | 4 | 2c | 6,11 and 16 | 3 | 0 | No E2 | Integrated |
| Larynx | 3 | 3 | 6,11 and 16 | 4 | 0 | No E2 | Integrated |
| Larynx | 3 | 0 | 6,11 and 16 | 3 | 0 | No E2 | Integrated |
| Oral cavity | 2 | 0 | 6,11,16,18 | ND* | 0 | No E2 No E6 | NA** |
| Oral cavity | 3 | 0 | 6,11 and 16 | ND* | 0 | No E2 No E6 | NA** |
| Nasopharynx | 4 | 3 | 11, 16, 51 | ND* | 0 | No E2 No E6 | NA** |
| Oral cavity | 1 | 0 | 6,11,16,53 | 4 | 0 | No E2 | Integrated |
| Larynx | 2 | 0 | 6,11 and 16 | 2 | 0 | No E2 | Integrated |
| Hypopharynx | 2 | 3 | 6,11,16,31 | ND* | 0 | No E2 No E6 | NA** |
| Oropharynx | 2 | 2b | 6,11,16,31 | 3 | 0 | No E2 | Integrated |
| Larynx | 2 | 0 | 6,16,18,31 | 3 | 0 | No E2 | Integrated |
| Oral cavity | 2 | 1 | 6,16,18,31 | 4 | 0 | No E2 No E6 | NA** |
| Nasopharynx | 3 | 0 | 6,11,16,31 | ND* | 0 | No E2 No E6 | NA** |
ND*
Not determined.
NA**
Not applicable.