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. 2020 Aug 10;13:7921–7932. doi: 10.2147/OTT.S256161

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© 2020 Zang et al.

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JNK3 regulates the tumorigenesis of prostate cancer cells. JNK3 was knocked down by two separate siRNAs in two prostate cancer cell lines. After 48 h, the expression of JNK3 was detected by qRT-PCR (A) and Western blot (B). Cell growth was measured by CCK8 assay in PC-3 (C) and DU145 cells (D). Cell migration was detected by wound healing assay (E). Cell invasion was detected by Transwell assay (F). Cell apoptosis was measured by FACS (G). *p<0.05, **p<0.01 compared to the corresponding controls.