Table 1.
Demographic and clinical characteristics in Crohn’s-disease patients with primary strictures receiving endoscopic stricturotomy (ESt) and ileo-colonic resection (ICR)
| Characteristic | ESt |
ICR |
P-value | ||
|---|---|---|---|---|---|
| N | Statistics | N | Statistics | ||
| Female gender | 13 | 9 (69.2) | 32 | 22 (68.8) | 0.97 |
| Caucasian | 13 | 13 (100) | 32 | 31 (96.9) | 0.52 |
| Smoking | 0.34 | ||||
| Current | 13 | 2 (15.4) | 32 | 7 (21.9) | |
| Ex | 13 | 4 (30.8) | 32 | 4 (12.5) | |
| Family history | |||||
| Inflammatory bowel disease | 13 | 1 (7.7) | 32 | 3 (9.4) | 0.86 |
| Colon cancer | 13 | 4 (30.8) | 32 | 2 (6.2) | 0.03 |
| Weight, kg | 13 | 68.0 ± 25.9 | 29 | 64.9 ± 15.1 | 0.12 |
| Body mass index, kg/m2 | 13 | 22.7 ± 7.2 | 29 | 23.2 ± 4.7 | 0.11 |
| Age at Crohn’s diagnosis, year | 13 | 29.1 ± 9.9 | 32 | 25.6 ± 16.2 | 0.86 |
| Extra-intestinal manifestations | 13 | 4 (30.8) | 32 | 7 (21.9) | 0.53 |
| History of perianal involvement | 13 | 4 (30.8) | 32 | 7 (21.9) | 0.53 |
| Medication | |||||
| 5-Aminosalicylic acid | 13 | 6 (46.2) | 32 | 26 (81.2) | 0.02 |
| Corticosteroids | 13 | 4 (30.8) | 32 | 22 (68.8) | 0.02 |
| Immunomodulator | 13 | 5 (38.5) | 32 | 17 (53.1) | 0.37 |
| Biologics | 13 | 5 (38.5) | 32 | 12 (37.5) | 0.95 |
| Symptoms | 11 | 9 (81.8) | 30 | 30 (100) | 0.91 |
| Diarrhea/urgency | 11 | 6 (54.5) | 30 | 20 (66.7) | 0.48 |
| Constipation | 11 | 6 (54.5) | 30 | 3 (10.0) | 0.002 |
| Abdominal pain | 11 | 6 (54.5) | 30 | 24 (80.0) | 0.10 |
| Bloating | 11 | 1 (9.1) | 30 | 3 (10.0) | 0.93 |
| Nausea/vomiting | 11 | 5 (45.5) | 30 | 12 (40.0) | 0.75 |
| Bleeding | 11 | 1 (9.1) | 30 | 7 (23.3) | 0.31 |
| Radiological presentation | |||||
| Pre-stenosis proximal dilation | 11 | 1 (9.1) | 31 | 21 (67.7) | 0.001 |
| Bowel wall thickness | 11 | 10 (90.9) | 32 | 32 (100) | 0.26 |
| Mucosal enhancement | 11 | 8 (72.7) | 26 | 23 (88.5) | 0.24 |
| Age at stricture diagnosis, year | 13 | 37.9 ± 8.7 | 32 | 33.5 ± 15.3 | 0.94 |
| Duration from Crohn’s diagnosis to stricture diagnosis, year | 13 | 5.1 (0.8–14.9) | 32 | 8.1 (2.8–12.4) | 0.57 |
| Age at treatment, year | 13 | 40.3 ± 9.8 | 32 | 33.7 ± 15.2 | 0.73 |
| Duration from stricture diagnosis to treatment, year | 13 | 0.5 (0–5.5) | 32 | 0.2 (0.1–0.6) | 0.90 |
| Length of stricture, cm | 9 | 2.4 ± 0.9 | 32 | 3.0 ± 1.1 | 0.17 |
| Ulceration | 13 | 3 (23.1) | 23 | 9 (39.1) | 0.33 |
| Multiple strictures | 13 | 6 (46.2) | 32 | 9 (28.1) | 0.25 |
| Degree of stricture | 0.26 | ||||
| Mild resistance to scope | 13 | 0 (0) | 15 | 1 (6.7) | |
| Moderate resistance to scope | 13 | 0 (0) | 15 | 1 (6.7 ) | |
| Severe resistance to scope | 13 | 0 (0) | 15 | 2 (13.3) | |
| Not transversable to scope | 13 | 13 (100) | 15 | 11 (73.3) | |
Values are presented as mean ± standard deviation, median (interquartile range), or n (%).