Figure 2.

Representative examples of corneal epithelial thickness and maximal limbal epithelial thickness (mLET) using anterior segment optical coherence tomography (AS-OCT) in the control subjects and patients with limbal stem cell deficiency (LSCD) in different stages of severity. Slit-lamp photos (left), fluorescein staining patterns (middle left), AS-OCT images of the central (middle right), and mLET (right) in the control subjects and patients with LSCD are shown. The epithelium in the normal eye is transparent and devoid of fluorescein staining (top left). In LSCD, affected area exhibited stippled fluorescein staining in a whorl-like pattern or pooling (bottom left 3 panels). There was epithelial thinning as outlined by the fluorescein staining in the cornea and affected limbal regions (left middle bottom 3 panels).