TABLE.
Clinical Characteristics of Patients with Limbal Stem Cell Deficiency and Normal Controls
| Control group | LSCD group | P* | Subgroup comparison P<0.05 | ||||
|---|---|---|---|---|---|---|---|
| All | Stage I | Stage II | Stage III | ||||
| Eyes (%) | 52 | 69 | 27(39.7) | 27(39.7) | 14(20.6) | ||
| BCVA logMAR | 0.0±0.0 | 1.1±0.7 | 0.6±0.9 | 1.4±1.3 | 1.6±1.0 | <0.001 | 1, 2, 3, 4, 5 |
| Clinical Score | 0±0 | 5.35±2.76 | 2.4±1.1 | 6.3±1.1 | 9.0±1.0 | <0.001 | 1, 2, 3, 4, 5, 6 |
| OCT-CET3 (μm) | 55.0±3.0 | 41.6±10.8 | 49.5±2.9 | 38.9±9.6 | 32.8±12.2 | <0.001 | 1,2, 3, 4, 5, 6 |
| mLET (μm) | |||||||
| Superior | 108.4±23.8 | 68.0±21.7 | 72.8±19.9 | 64.3±24.3 | 65.8±19.5 | <0.001 | 1, 2, 3 |
| Inferior | 102.0±27.0 | 71.8±21.4 | 71.3±16.5 | 75.3±26.3 | 66.0±19.0 | <0.001 | 1, 2, 3 |
| Nasal | 86.7±14.6 | 69.0±17.5 | 72.9±19.3 | 70.6±16.5 | 58.4±11.4 | <0.001 | 1, 2, 3, 5, 6 |
| Temporal | 84.6±14.1 | 70.3±17.4 | 78.0±15.9 | 66.3±16.7 | 63.1±16.9 | <0.001 | 2, 3, 4, 5 |
P values of ANOVA performed among the control group and LSCD groups; In subgroup comparison, 1. Control vs. Stage I; 2. Control vs. Stage II; 3. Control vs. Stage III; 4. Stage I vs. Stage II; 5. Stage I vs. Stage III; 6. Stage II vs. Stage III.