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. Author manuscript; available in PMC: 2021 Sep 1.
Published in final edited form as: Pharmacol Ther. 2020 May 29;213:107591. doi: 10.1016/j.pharmthera.2020.107591

Figure 1. Tumor-cell-intrinsic and tumor-cell-extrinsic roles of lncRNAs.

Figure 1.

Intrinsic factor roles of lncRNAs regulate antigen processing machinery and constitutive PD-L1 expression in cancer cells; Extrinsic factors roles of lncRNAs regulate the activity of tumor microenvironment immune cells, such as TAM, CD8+, NK cells, Th1/Th2, DC, and MDSC.