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. 2020 May 28;8(8):e1279. doi: 10.1002/mgg3.1279

FIGURE 1.

FIGURE 1

An illustration of speculated embryo and placenta development process of the fetus. The karyotype for the paternal sperm may be an unusual diploid gamete (25,XX,+21) and zygote is likely to be a double‐trisomy (48,XXX,+21). After the fifth cleavage, the zygote grows into a morula and then into a blastocyst. The blastocyst contains two major part of compositions. One is the inner cell mass (yellow), which develops into the embryo (the homogeneous 47,XXX). The other is trophoblast cells (blue), which develops with some inner cell mass into the placenta (the mosaic 47,XXX, 47,XX,+21, or 48,XXX,+21)