Fig. 5. COMMD4 is required for survival following the exposure of NSCLC cells to DNA damaging agents.
a–c Clonogenic cell viability assays in HBEC3-KT, H460 and H1975 NSCLC cells transfected with control or COMMD4 siRNA (#2 or #3) and treated with varying doses of irradiation (IR). d–f Clonogenic cell viability assays in HBEC3-KT, H1975 and CRL5889 cells transfected with control or COMMD4 siRNA (#2 or #3) and treated with varying doses of camptothecin as shown. Asterix (*) denotes p < 0.05. n.s; not significant. Error bars represent mean ± SD from three independent experiments.