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. 2020 Aug 8;11(8):653. doi: 10.1038/s41419-020-02846-7

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 5 — a Determination of plasma LXA₄ concentration in mice. Plasma samples were collected from mice 2 and 6 weeks post-75 Gy IR and their LXA₄ levels were measured by ELISA. b LOX enzyme activity was measured in mice (left) and MLE12 cells (right) using a Lipoxygenase Assay kit, according to the manufacturer’s instructions. ALOX12 and ALOX15 mRNA levels in the irradiated lung tissues of mice (c) and MLE12 cells (d) measured using quantitative real-time PCR. Data are expressed as the mean ± standard error (n = 3‒5, *p < 0.05, **p < 0.01, and ***p < 0.001).