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. 2020 Aug 18;10:13969. doi: 10.1038/s41598-020-70886-2

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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EIF3J-AS1 levels are increased in ECa. (A) Expression of EIF3J-AS1 in ECa and paired normal tissue samples from the GEPIA data. (B) Expression of EIF3J-AS1 was measured in ECa and paired normal tissue samples via qRT-PCR. (C) Histogram and pie chart of the proportions of Eca samples in which EIF3J-AS1 expression was up-regulated (64/182, 35.16%, blue), down-regulated (38/182, 20.88%, green), or no change (80/182, 43.96%, red). Log2 (T/N) expression value > 1 as higher expression, which < − 1 as lower expression, and between − 1 and 1 as no significant change. (D) Expression of EIF3J-AS1 was measured in ECa and control cell lines. (E, F) Overall survival (OS) and Disease-free survival (DFS) in ECa patients. Kaplan Meier (KM) curves were plotted for survival analysis. p-value *< 0.05; **< 0.01; ***< 0.001.