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. 2020 Aug 18;11(8):642. doi: 10.1038/s41419-020-02903-1

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 2 — a, b The knockdown efficiency of DNER in MCF-7 and MDA-MB-468 cells. c Cell growth was measured by CCK-8 assay after DNER knockdown in two BC cell lines. d Wound healing assay was used to determine the migratory ability of BC cells with DNER knockdown. e The invasion capacity of BC cells with knockdown of DNER was confirmed by Transwell assay. Down: Quantitative analysis of invasion ratio was shown. The values are the mean ± SD from three independent experiments. ^nsp > 0.05, *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001 vs the control group.