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. 2020 Aug 18;11(8):642. doi: 10.1038/s41419-020-02903-1

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 3 — a, b EMT-related proteins E-cadherin, N-cadherin, Vimentin, and Snail were detected by western blotting in DNER knockdown cells. Right: quantitative analysis of the optical density ratio of E-cadherin, N-cadherin, Vimentin and Snail compared with β-actin are shown. c, d EMT-related protein levels were measured by western blotting after DNER overexpression in BC cells. Right: quantitative analysis of the optical density ratio of E-cadherin, N-cadherin, Vimentin, and Snail compared with β-actin are shown. e, f DNER was overexpressed in DNER knockdown cells, and then western blotting detected the expression of EMT-related proteins. The values are the mean ± SD from three independent experiments. *p < 0.05, **p < 0.01, ***p < 0.001 vs the corresponding group.