Table 1.
Clinicopathological associations of DNER expression in breast cancer.
| Variables | Low N = 92 (%) |
High N = 114 (%) |
P value* |
|---|---|---|---|
| Age at diagnosis, years | 0.664 | ||
| ≤50 | 21 (22.8) | 29 (25.4) | |
| >50 | 71 (77.2) | 85 (74.6) | |
| Grade | 0.043 | ||
| Well | 17 (18.5) | 9 (7.9) | |
| Moderately | 24 (26.1) | 26 (22.8) | |
| Poorly | 51 (55.4) | 79 (69.3) | |
| Tumour size (cm) | 0.073 | ||
| ≤2 | 47 (51.1) | 44 (38.6) | |
| >2 | 45 (48.9) | 70 (61.4) | |
| Lymph node metastasis | 0.759 | ||
| Negative | 35 (38.0) | 41 (36.0) | |
| Positive | 57 (62.0) | 73 (64.0) | |
| Vascular invasion | 0.098 | ||
| Negative | 78 (84.8) | 86 (75.4) | |
| Positive | 14 (15.2) | 28 (24.6) | |
| ER | 0.152 | ||
| Negative | 69 (75.0) | 75 (65.8) | |
| Positive | 23 (25.0) | 39 (34.2) | |
| PR | 0.034 | ||
| Negative | 55 (59.8) | 84 (73.7) | |
| Positive | 37 (40.2) | 30 (26.3) | |
| HER2 | 0.381 | ||
| Negative | 58 (63.0) | 65 (57.0) | |
| Positive | 34 (37.0) | 49 (43.0) | |
| Ki67 | 0.535 | ||
| <14 % | 72 (78.3) | 85 (74.6) | |
| ≥14 % | 20 (21.7) | 29 (25.4) | |
| Recurrence | 0.041 | ||
| No | 83(90.2) | 91(79.8) | |
| Yes | 9(9.8) | 23(20.2) |
*P values calculated by log-rank testing; bold if statistically significant, P < 0.05.
ER oestrogen receptor, PR progesterone receptor, HER2 human epithelial growth factor receptor-2.