Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2020 Aug 12;11:804. doi: 10.3389/fneur.2020.00804

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2020 Dewan, Serdar, van de Looij, Kowallick, Hadamitzky, Endesfelder, Fandrey, Sizonenko, Herz, Felderhoff-Müser and Bendix.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

Long-term microstructural development after neonatal hyperoxia-induced brain-injury. Diffusion tensor imaging (DTI) was performed in 5 months old rats, which were exposed to behavior tests at the age of 2 and 4 months. From P3 to P5, rats were either exposed to normoxia [21% oxygen (NO)] or hyperoxia (80% oxygen (HO)] and treated with Epo (4 × 5000 IU/kg body weight per day from P3 to P6) or with an equal amount of normal saline. (A) For each treatment group, representative maps for axial diffusivity (AD, D_//), radial diffusivity (RD, D_⊥), mean diffusivity (MD), fractional anisotropy (FA) and direction encoded colour maps (DEC) derived from DTI are shown. Diffusivity values for MD, AD (D_//), RD (D_⊥) and FA are displayed for (B) corpus callosum, and (C) external capsule. *p < 0.05, **p < 0.01, n = 8 rats/group.