TABLE 2.

Correlation between TEP U1, U2, U5 expression and clinicopathologic characteristics of lung cancer patients.

Characteristics		Cases No. (%)	U1			U2			U5
			Low	High	p	Low	High	p	Low	High	p
Gender	Male	252 (66.0)	111	141	0.001	120	132	0.195	116	136	0.031
	Female	130 (34.0)	80	50		71	59		75	55
Age (y)	≥62	199 (52.1)	93	106	0.183	97	102	0.609	97	102	0.609
	<62	183 (47.9)	98	85		94	89		94	89
Smoking	Yes	187 (49.0)	79	108	0.003	84	103	0.052	83	104	0.032
	No	195 (51.0)	112	83		107	88		108	87
Drinking	Yes	126 (33.0)	47	79	<0.0001	58	68	0.276	61	65	0.663
	No	256 (67.0)	144	112		133	123		130	126
Histology	NSCLC
	AC	222 (58.1)	120	102	0.172	114	108	0.693	127	95	0.002
	SCC	88 (23.0)	40	48		43	45		33	55
	Others	12 (3.1)	6	6		7	5		6	6
	SCLC	51 (13.4)	24	27		25	26		22	29
	Unknown	9 (2.4)
Tumor size	≥8.788 cm3	145 (38.0)	69	76	0.124	70	75	0.287	64	81	0.018
	<8.788 cm3	143 (37.4)	81	62		78	65		83	60
	Unknown	94 (24.6)
T stage	Tis	11 (2.9)	9	2	0.03	8	3	0.264	10	1	0.007
	T1	91 (23.8)	51	40		52	39		55	36
	T2	122 (31.9)	62	60		58	64		57	65
	T3	44 (11.5)	24	20		21	23		21	23
	T4	88 (23)	34	54		40	48		37	51
	Unknown	26 (6.9)
TNM stage	Stage 0	11 (2.9)	9	2	0.001	8	3	0.021	10	1	0.001
	Stage I	64 (16.8)	44	20		41	23		43	21
	Stage II	24 (6.3)	14	10		14	10		12	12
	Stage III	87 (22.8)	42	45		41	46		37	50
	Stage IV	187 (49.0)	79	108		81	106		85	102
	Unknown	9 (2.3)
LN metastasis	Yes	253 (66.2)	107	146	<0.0001	116	137	0.012	113	140	0.001
	No	106 (27.7)	72	34		64	42		67	39
	Unknown	23 (6)
Distant metastasis	Yes	187 (49.0)	79	108	0.002	81	106	0.013	85	102	0.079
	No	187 (49.0)	109	78		105	82		102	85
	Unknown	8 (2)

*Chi-square test was used. Bold value, p< 0.05; NSCLC, non-small cell lung cancer; AC, adenocarcinoma; SCC, squamous cell carcinoma; SCLC, small cell lung cancer.