. 2020 Aug 18;6:21. doi: 10.1038/s41526-020-00111-x

Table 1.

Bone mineral density and leg lean and fat tissue mass before and after long-duration spaceflight with standard of care exercise or Sprint exercise prescription.

	CON		SPRINT
	Preflight	Postflight	Preflight	Postflight
Lumbar spine (g cm⁻²)	1.088 ± 0.024	1.068 ± 0.024*	1.067 ± 0.032	1.053 ± 0.032*
Pelvis (g cm⁻²)	1.289 ± 0.034	1.247 ± 0.035*	1.249 ± 0.047	1.208 ± 0.047*
Total hip (g cm⁻²)	1.054 ± 0.026	1.023 ± 0.026*	1.045 ± 0.036	1.027 ± 0.036*
Trochanter (g cm⁻²)	0.797 ± 0.023	0.771 ± 0.023*	0.786 ± 0.032	0.774 ± 0.032*
Femoral neck (g cm⁻²)	0.860 ± 0.025	0.846 ± 0.025*	0.862 ± 0.034	0.845 ± 0.034*
Both legs (g cm⁻²)	1.328 ± 0.026	1.323 ± 0.026	1.260 ± 0.036	1.247 ± 0.036
Calcaneus (g cm⁻²)	0.729 ± 0.025	0.722 ± 0.025*	0.677 ± 0.034	0.666 ± 0.034*
Leg lean mass (kg)	18.77 ± 0.68	18.64 ± 0.68	18.37 ± 0.94	18.28 ± 0.04
Leg fat mass (kg)	6.10 ± 0.43	5.75 ± 0.43*	6.02 ± 0.62	5.69 ± 0.62*

Data are mean ± SE and were collected via DXA approximately 90 days preflight and 7–14 days postflight. No significant group × time interaction effects were detected (P > 0.05). CON control group that performed the ISS standard of care exercise prescription, SPRINT experimental group that performed a high intensity/lower volume exercise prescription.

*Simple main effect for time relative to preflight (P < 0.05).