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. 2020 Aug 12;11:900. doi: 10.3389/fgene.2020.00900

TABLE 5.

Performances of various tools on human NA12878 genome sequencing data.

Dataset Tool Deletion rate (%) Insertion rate (%) Mismatch rate (%) Error rate (%)
NA12878 Chr. 1-21 and Chr. X Total 2,200 reads Albacore (default) 12.32 4.53 5.88 22.74
DeepNano 11.67 5.15 5.53 22.36 (0.38)
Chiron 9.46 4.21 4.47 18.13 (4.61)
Scrappie eventsa 10.43 4.39 4.09 18.89 (3.84)
Scrappie rawb 9.15 4.67 4.22 19.01 (3.73)
NanoReviser (low coverage) 9.65 4.94 4.38 18.97 (4.76)
NanoReviser (local) 8.64 4.81 4.35 17.80 (4.93)
NanoReviser 8.84 4.40 3.83 17.07(−5.66)

aScrappie events could only basecall 2,186 reads, we use the default reads basecalled by Albacore to instead the miss-basecalled 14 reads. bScrappie raw could only basecall 1,625 reads, we use the default reads basecalled by Albacore to instead the miss-basecalled 575 reads. The number in bold denotes the lowest error rate in the corresponding columns.