Table 2.
Hemodynamic parameters by recording
| Parameter | Standing | SSMD | SSMS | p‐value |
|---|---|---|---|---|
| CBFv MCA (cm/s) | 59.1 ± 8.5 b , c | 64.7 ± 10.4 | 61.6 ± 8.8 b | <.01 |
| MAP (mmHg) | 92.6 ± 10.7 b , c | 97.9 ± 12.4 | 98.3 ± 13.5 | <.01 |
| Systolic BP (mmHg) | 121.4 ± 17.4 c | 130.6 ± 24.8 | 130.5 ± 24.6 | <.01 |
| Diastolic BP (mmHg) | 80.6 ± 9.1 | 82.4 ± 9.7 | 84.2 ± 11.3 | .01 |
| HR (bpm) | 78.7 c (73.5–88.7) | 86.1 (79.1–93.9) | 83.7 (77.7–98.7) | <.01 |
| EtCO2 (mmHg) | 35.5 ± 3.2 b | 38.3 ± 3.7 | 36.6 ± 3.6 b | .01 |
| ΔMAP younger group (mmHg) | — | 30.55 ± 13.41 | 12.96 ± 8.40 | <.001 |
| ΔMAP older group (mmHg) | — | 37.83 ± 18.45 | 22.21 ± 15.55 | <.001 |
| ΔCBFv younger group (cm/s) | — | 39.70 ± 12.15 | 13.66 ± 4.94 | <.001 |
| ΔCBFv older group (cm/s) | — | 38.97 ± 8.68 | 18.88 ± 12.83 | <.001 |
Normally distributed data are given as mean ± SD, non‐normally distributed data are given as median (IQR). p‐values were determined by repeated measured ANOVA and post hoc Tukey tests to compare between recordings. HR was compared using Friedman's test and Dunn's multiple comparison tests.
Abbreviations: BP, blood pressure; CBFv, cerebral blood flow velocity; EtCO2, end‐tidal CO2; HR, heart rate; MAP, mean arterial pressure; MCA, middle cerebral artery; ΔCBFv, range of CBFv excursion during SSM; ΔMAP, range of MAP excursion during SSM.
b
Reduced compared to SSMD.
c
Reduced compared to SSMS.