TABLE 2.
FSHD | Range (FSHD) | Control | Range (control) | p-value | |
Measures of sarcopenia | |||||
ALM (kg) | |||||
Males and females combined | 20.5 ± 4.4 | 15.3–27.5 | 26.5 ± 5.9 | 20.6–39.0 | 0.02 |
Males | 21.2 ± 4.7 | 15.3–27.5 | 27.7 ± 6.1 | 20.6–39.0 | 0.03 |
Females | 17.7 ± 1.9 | 16.4–19.1 | 22.0 ± 1.1 | 21.1–22.8 | 0.15 |
Additional measures of lean mass | |||||
Whole body lean mass (kg) | |||||
Males and females combined | 47.6 ± 6.0 | 40.5–57.3 | 56.6 ± 11.1 | 45.9–78.8 | 0.05 |
Males | 49.1 ± 5.8 | 40.5–55.0 | 58.8 ± 11.5 | 45.9–78.8 | 0.05 |
Females | 41.7 ± 1.7 | 42.9–57.3 | 47.7 ± 0.6 | 47.2–48.1 | 0.10 |
Total arms lean mass (kg) | |||||
Males and females combined | 5.4 ± 1.1 | 43.9–73.9 | 7.5 ± 2.1 | 4.4–12.5 | < 0.01 |
Males | 5.7 ± 1.1 | 44.6–73.9 | 8.1 ± 2.1 | 5.1–12.5 | 0.01 |
Females | 4.4 ± 0.04 | 43.9–44.5 | 5.5 ± 0.6 | 4.4–5.9 | 0.22 |
Total legs lean mass (kg) | |||||
Males and females combined | 15.1 ± 3.5 | 10.8–20.5 | 19.0 ± 3.9 | 14.0–26.5 | 0.03 |
Males | 15.5 ± 3.8 | 10.8–20.5 | 19.6 ± 4.2 | 14.0–16.5 | 0.06 |
Females | 13.3 ± 2.0 | 11.9–14.7 | 16.4 ± 0.6 | 16.0–16.8 | 0.25 |
Additional measures of adiposity | |||||
Whole body fat mass (kg) | |||||
Males and females combined | 33.7 ± 10.1 | 21.8–49.6 | 22.0 ± 6.9 | 11.2–49.6 | <0.01 |
Males | 33.5 ± 9.4 | 21.8–49.6 | 19.7 ± 5.3 | 11.2–49.6 | <0.01 |
Females | 34.7 ± 17.0 | 22.7–46.7 | 31.1 ± 4.9 | 27.7–34.7 | 0.82 |
Total arms fat mass (kg) | |||||
Males and females combined | 3.2 ± 0.9 | 2.1–5.0 | 2.5 ± 0.9 | 1.4–4.9 | 0.09 |
Males | 3.1 ± 0.9 | 2.1–5.0 | 2.2 ± 0.5 | 1.4–4.9 | 0.02 |
Females | 3.4 ± 1.2 | 2.5–4.3 | 3.8 ± 0.6 | 3.4–4.2 | 0.75 |
Total legs fat mass (kg) | |||||
Males and females combined | 10.7 ± 2.4 | 7.2–14.9 | 6.0 ± 1.6 | 3.1–12.1 | <0.01 |
Males | 10.3 ± 2.1 | 7.2–13.1 | 5.4 ± 1.1 | 3.1–12.1 | <0.01 |
Females | 12.2 ± 3.9 | 9.4–14.9 | 8.5 ± 0.1 | 8.4–8.5 | 0.40 |
When males and females are combined, individuals with FSHD had lower appendicular lean mass (ALM), arm lean mass and leg lean mass but greater body and leg fat mass. When separated by sex, only males with FSHD exhibited a significant difference in these measures. kg: kilogram; data are presented in mean ± SD.