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. 2019 Nov 21;26(4):202–208. doi: 10.5761/atcs.oa.19-00162

Table 2. Changes of each blood test.

T-cho (mg/dL) Pre 1M 2M 3M 4M 5M 6M

 Febuxostat 159.3 ± 4.7 160.5 ± 4.4 167.6 ± 4.1 165.4 ± 5.5 167.9 ± 5.0 164.4 ± 4.8 159.5 ± 4.5
 Topiroxostat 166.3 ± 5.2 163.6 ± 5.2 164.0 ± 5.1 164.6 ± 4.6 167.2 ± 5.0 163.1 ± 4.9 162.6 ± 5.4
TG (mg/dL) Pre 1M 2M 3M 4M 5M 6M
 Febuxostat 118.8 ± 8.5 114.8 ± 7.5 116.8 ± 8.3 119.0 ± 8.8 114.4 ± 6.8 117.0 ± 8.0 105.0 ± 7.4
 Topiroxostat 135.7 ± 13.3 139.2 ± 14.2 121.0 ± 9.3 139.6 ± 12.7 119.4 ± 8.0 111.3 ± 7.8 122.9 ± 9.1
L/H Pre 1M 2M 3M 4M 5M 6M
 Febuxostat 1.67 ± 0.10 1.64 ± 0.10 1.64 ± 0.10 1.61 ± 0.10 1.63 ± 0.10 1.61 ± 0.10 1.60 ± 0.10
 Topiroxostat 1.74 ± 0.11 1.71 ± 0.10 1.71 ± 0.10 1.75 ± 0.12 1.74 ± 0.13 1.63 ± 0.11 1.66 ± 0.10
RLP-cho(mg/dL) Pre 3M 6M
 Febuxostat 4.97 ± 0.58 4.99 ± 0.59 4.14 ± 0.50
 Topiroxostat 4.87 ± 0.59 5.21 ± 0.59 4.57 ± 0.46
EPA/AA Pre 3M 6M
 Febuxostat 0.53 ± 0.06 0.60 ± 0.07 0.61 ± 0.07
 Topiroxostat 0.63 ± 0.06 0.62 ± 0.07 0.58 ± 0.06
BNP (pg/mL) Pre 3M 6M
 Febuxostat 124.1 ± 29.3 108.4 ± 26.5 110.6 ± 29.9
 Topiroxostat 116.6 ± 0.04 125.3 ± 31.7 149.8 ± 36.4
hs-CRP (mg/dL) Pre 1M 2M 3M 4M 5M 6M
 Febuxostat 0.21 ± 0.06 0.38 ± 0.19 0.23 ± 0.04 0.19 ± 0.03 0.28 ± 0.08 0.32 ± 0.07 0.23 ± 0.05
 Topiroxostat 0.19 ± 0.03 0.23 ± 0.05 0.33 ± 0.09 0.30 ± 0.09 0.24 ± 0.07 0.41 ± 0.17 0.31 ± 0.07

BNP: B-type natriuretic peptide; hs-CRP: high-sensitivity C-reactive protein; T-cho: total cholesterol; TG: triglyceride; L/H: high-density lipoprotein/low-density lipoprotein; RLP-cho: remnant-like particles-cholesterol; EPA/AA: eicosapentaenoic acid/arachidonic acid