Table 3.
Description of the regions associated with the fatty acid composition in intramuscular fat and the candidate genes contained within them.
Region | Chra | Start (bp)b | End (bp)b | No. SNPsc | Top SNP | MAFd | p-value | FDR | Trait | Candidate genee |
---|---|---|---|---|---|---|---|---|---|---|
LD1 | 4 | 19,019,566 | 21,057,452 | 2 | rs80910044 | 0.177 | 2.42 × 10−6 | 8.92 × 10−2 | C20:4(n-6)/C20:3(n-6) | ENPP2; EXT1; NOV |
LD2 | 4 | 122,756,546 | 124,979,309 | 3 | rs81347340; rs80915252 | 0.437 | 1.18 × 10−5 | 7.65 × 10−2 | C20:3(n-3) | ABCD3; GCLM |
LD3 | 13 | 175,539,436 | 181,652,057 | 3 | rs81441592 | 0.066 | 1.81 × 10−6 | 6.96 × 10−2 | C20:3(n-3) | LIPI; NRIP1; ssc-let-7c |
LD4 | 14 | 109,946,218 | 114,621,937 | 21 | rs335655209 | 0.115 | 1.04 × 10−7 | 7.51 × 10−4 | C18:1(n-9)/C18:0*; MUFA/SFA | ELOVL3; SCD |
LD5 | 14 | 140,151,934 | 141,755,446 | 6 | rs318740977; rs80814938; rs80883500 | 0.083 | 3.58 × 10−6 | 3.27 × 10−2 | C18:0 | BNIP3; CYP2E1; ECHS1 |
LD6 | 17 | 30,061,857 | 32,867,849 | 4 | rs324135473 | 0.148 | 2.65 × 10−6 | 9.16 × 10−2 | C20:0 | ABHD12; ACSS1; PANK2; ssc-mir-103–2 |
aSus scrofa chromosome.
bPosition on the chromosome where the region begins (start) and finishes (end).
cNumber of significant SNPs found inside the region.
dMinor allele frequency.
eList of suggested genes for explaining part of the phenotypic variance of the trait.
*Indicates the most significant trait. If there is more than one associated trait on the region, the p-value and FDR of the top SNP refer to this trait.