Table 1.
Distribution of routine TB diagnostic tests performed and results of routine TB diagnostic tests and Xpert MTB/RIF Ultra.
| Culture and/or PCR positive samplesa | Number of samples | Routine TB diagnostic tests (positive/total number) | Xpert Ultra | ||
|---|---|---|---|---|---|
| Microscopy | Routine PCR | Culture | |||
| Lymph node biopsy | 1 | 0/1 | 1/1 | 1/1 | 1/1 |
| Lymph node aspirate | 4 | 3/4 | 3/3 | 4/4 | 4/4 |
| Pus samples | 2 | 0/2 | 2/2 | 1/2 | 2/2 |
| Other biopsies (pleura) | 1 | 0/1 | 0/1 | 1/1 | 1/1 |
| Fluid samples | 1 | 0/1 | 0/1 | 1/1 | 0/1 |
| Gastrointestinal lavage | 1 | 0/1 | 1/1 | 1/1 | 1/1 |
| Total | 10 | 3/10 | 7/9 | 9/10 | 9/10 |
| Samples per inclusion site | |||||
| Samples from HUH | 8 | 3/8 | 5/7 | 8/8 | 7/8 |
| Samples from SUH | 2 | 0/2 | 2/2 | 1/2 | 2/2 |
| Culture and PCR negative samplesb | |||||
| Lymph node biopsy | 4 | 1/4 | 0/1 | 0/4 | 1/4 |
| Lymph node aspirate | 11 | 2/11c | 0/3 | 0/11 | 0/11 |
| Pus samples | 14 | 1/14d | 0/1 | 0/14 | 0/14 |
| Other biopsies | 13 | 0/13 | 0/4e | 0/13 | 0/13 |
| Fluid samples | 28 | 0/17 | 0/3 | 0/28 | 0/28 |
| Gastrointestinal lavage | 2 | 0/1 | N/A | 0/2 | 0/2 |
| Total | 72 | 4/60 | 0/12 | 0/72 | 1/72 |
| Samples per inclusion site | |||||
| Samples from HUH | 58 | 3/53 | 0/9 | 0/58 | 0/58 |
| Samples from SUH | 14 | 1/7 | 0/3 | 0/14 | 1/14 |
HUH Haukeland University Hospital, SUH Stavanger University Hospital.
aTwo of the samples (culture positive biopsy and culture positive fluid sample) are from the same TB case.
bIncludes three samples from clinically diagnosed TB cases (one pus sample, one biopsy and one lymph node aspirate).
cThe two microscopy positive samples were both culture positive for Mycobacterium avium.
dMicroscopy positive sample was culture positive for Mycobacterium avium.
eFive culture negative biopsy samples were subjected to routine PCR, of which one PCR test result was indeterminate (technical failure). The indeterminate PCR result has been excluded from the results and analysis.